Blogspot - somatic-gene-therapy.blogspot.com - Somatic Gene Therapy
General Information:
Latest News:
Somatic Gene Therapy 10 Apr 2011 | 11:43 pm
Inborn errors of metabolism, like most disease, have both genetic and environmental components. Current therapy for inborn errors of metabolism focuses on the diagnosis of a genetic defect before the ...
Conclusion 2 Dec 2010 | 01:15 am
Gene therapies are currently being studied in more than 50 clinical trials. This method holds considerable promise for many inborn errors of metabolism. Gene therapy for inborn errors of metabolism re...
Towards Clinical Applications 2 Dec 2010 | 01:13 am
The efficacy of gene therapy will ultimately need to be assessed and demonstrated relative to conventional therapeutics. While it is widely believed that many inborn errors of metabolism may come to b...
Regulatory Considerations 2 Dec 2010 | 01:10 am
The intense social discourse conserning the propriety and etical implications of gene therapy has been largely resolved with the realization that somatic gene therapy is in principle no different than...
Clinical Indications 2 Dec 2010 | 01:08 am
The first clinical trials using retroviral vectors demonstrated the feasibility and social and regulatory acceptance of gene transfer into human subject. The initial trials have greatly expanded inter...
Current Clinical Trials 2 Dec 2010 | 01:06 am
Since the commencement of the first clinical trial involving gene transfer into human subjects in 1989, more than 100 patients have been treated and more than 100 patients have been treated and more t...
DNA Vector Delivery 2 Dec 2010 | 12:55 am
It is also possible to delivery DNA vectors directly to cells withouth the use of viruses. This involves the application of pharmaceutical methods for drug delivery to target DNA vectors to specific c...
Cell Based Therapy 2 Dec 2010 | 12:52 am
Organ transplantation in itself o form of gene therapy in which alloogenic cells containing a normal gene are implanted into the body. Genetic manipulation may be used to enhance transplantation ther...
Viral Vector Delivery 2 Dec 2010 | 12:49 am
The initial strategies for gene therapy involved the construction of viral vectors in which the expression vector was packaged into a virus particle that was capable of invecting cells. The premise of...
Vectors 2 Dec 2010 | 12:44 am
The function of a vector is to control how much of the therapeutic product is produced and where in the body it is produced. Effective gene therapy requires that a therapeutic gene be introduced into ...
