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Diagnostic gynaecological and obstetric pathology: an atlas and text 17 Oct 2012 | 05:16 pm

Reichert has managed to compile an invaluable bench side manual which does more than serve as an aide memoire. The text avoids confusing the key decisions that real life surgical pathologists need to ...

Marginal zone B-cell lymphoma in true trilineage haematopoietic tissue within heterotopic ossification of a surgical scar 17 Oct 2012 | 05:16 pm

We would like to describe an unusual location of marginal zone B-cell lymphoma in a surgical scar. A 53-year-old patient was admitted for a painful, hard abdominal scar. A splenectomy trough midline ...

Expression of D-type cyclins in AL amyloidosis plasma cells 17 Oct 2012 | 05:16 pm

Introduction Amyloid light chain (AL) amyloidosis is a plasma cell (PC) disorder characterised by the overproduction of monoclonal immunoglobulin light chains (LC). It can be treated effectively with...

Familial haemophagocytic lymphohistiocytosis-related plasma cell neoplasm: a case report 17 Oct 2012 | 05:16 pm

Introduction Haemophagocytic lymphohistiocytosis (HLH) is a life-threatening syndrome sustained by extreme immunological activation and associated with specific symptoms and pathological findings ( b...

A rare case of gastric MALT lymphoma resistant to multiple treatment regimens 17 Oct 2012 | 05:16 pm

In general, patients with extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT) run an indolent clinical course and respond favourably to treatment. For example, ~70% of gastri...

Supported liquid extraction offers improved sample preparation for aldosterone analysis by liquid chromatography tandem mass spectrometry 17 Oct 2012 | 05:16 pm

Background To evaluate the accuracy and precision of a method for serum aldosterone using supported liquid extraction (SLE) for sample preparation instead of the more conventional liquid-liquid extra...

Retrospective review of diagnostic histopathology samples in research projects: transparency should be the practice with respect to diagnostic discord... 17 Oct 2012 | 05:16 pm

Retrospective review of diagnostic histopathology samples in secondary research projects may generate cases with discordance in diagnosis between the pathologist originally signing out the sample and ...

Elevated, combined serum free light chain levels and increased mortality: a 5-year follow-up, UK study 17 Oct 2012 | 05:16 pm

Aims Abnormal serum free light chain (FLC) ratios are diagnostically important in almost all plasma cell disorders. However, absolute increases in polyclonal FLC levels are often discarded as inconse...

Point-of-care monitoring of vitamin K-antagonists: validation of CoaguChek XS test strips with International Standard thromboplastin 17 Oct 2012 | 05:16 pm

Aims Many patients treated with vitamin K-antagonists (VKA) use point-of-care (POC) whole blood coagulometers for self-testing. The majority of patients in the Netherlands use one type of POC coagulo...

Performance evaluation of the Sysmex haematology XN modular system 17 Oct 2012 | 05:16 pm

Background The Sysmex XN haematology instrument performs automatic reflex testing, depending on sample results. A nucleated red blood cell (NRBC) count is provided on all samples. The instrument has ...

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